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Symbol
Name
ID
Bmp4
bone morphogenetic protein 4
MGI:88180
Phenotype annotations related to reproductive system
Darker colors indicate more annotations
Human Phenotypes
Female hypogonadism
Small scrotum
Cryptorchidism
Disease(s) Associated with BMP4
syndromic microphthalmia 6

Mouse Phenotypes
decreased primordial germ cell number
absent primordial germ cells
abnormal prostate gland anterior lobe morphology
abnormal seminiferous tubule morphology
seminiferous tubule degeneration
small testis
abnormal external female genitalia morphology
abnormal male reproductive system morphology
external male genitalia hypoplasia
reduced female fertility
abnormal fertility/fecundity
decreased litter size
Availability Mouse Genotype
Bmp4tm1.1Jlch/Bmp4tm1.1Jlch
Bmp4tm1Blh/Bmp4tm1Blh
Bmp4tm2Blh/Bmp4tm2Blh
Bmp4tm1.1Jlch/Bmp4+
Bmp4tm1Blh/Bmp4+
Bmp4tm1Blh/Bmp4+
Tg(Prdm14-Venus)1Sait/0
Bmp4tm2Blh/Bmp4+
Bmp4tm4Blh/Bmp4tm4Blh
Isl1tm1(cre)Sev/Isl1+  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory